Bioactivity | CCW16 is the covalent ligand for the E3 ubiquitin ligase RNF4. CCW16 can be used in the synthesis of protein degraders[1]. | ||||||||||||
Name | CCW16 | ||||||||||||
CAS | 2361138-33-0 | ||||||||||||
Formula | C22H20ClNO3 | ||||||||||||
Molar Mass | 381.85 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Ward CC, et, al. Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. |