| Bioactivity | CCHa1 peptide is a signaling peptide that plays a role in inhibiting sleep arousal. It is produced by enteroendocrine cells in the gut and modulates the animal's response to sensory inputs such as mechanical vibrations by acting on specific dopamine neurons in the brain, thereby helping to suppress arousal responses. CCHa1 peptide holds potential for research in fields related to sleep quality and sensory adaptation[1]. |
| Sequence | Gln-Ile-Asp-Ala-Asp-Asn-Glu-Asn-Tyr-Ser-Gly-Tyr-Glu-Leu-Thr |
| Shortening | QIDADNENYSGYELT |
| Formula | C73H106N18O31 |
| Molar Mass | 1731.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Titos I, et al. A gut-secreted peptide suppresses arousability from sleep. Cell. 2023 Mar 30;186(7):1382-1397.e21. doi: 10.1016/j.cell.2023.02.022. Epub 2023 Mar 22. Erratum in: Cell. 2023 May 11;186(10):2273-2274. |