| Bioactivity | CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). CC-99677 is extracted from patent WO2020236636, compound 1[1]. | ||||||||||||
| Target | MK2 | ||||||||||||
| Invitro | CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM)[1]. | ||||||||||||
| Name | CC-99677 | ||||||||||||
| CAS | 1887069-10-4 | ||||||||||||
| Formula | C22H20ClN5O3S | ||||||||||||
| Molar Mass | 469.94 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. WO2020236636 |