| Bioactivity | CBD3063 is a selective modulator of collapsin response mediator protein 2 (CRMP2). CBD3063 uncouples Cav2.2 from CRMP2. CBD3063 reverses neuropathic and inflammatory pain by reducing membrane expression of CaV2.2[1][2]. |
| CAS | 1281060-70-5 |
| Formula | C16H25N5O2 |
| Molar Mass | 319.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gomez K, et, al. A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2305215120. [2]. Allen HN, et, al. Uncoupling the CRMP2-CaV2.2 Interaction Reduces Pain-Like Behavior in a Preclinical Joint-Pain Model. J Pain. 2024 Sep 2:104664. |