| Bioactivity | CB2R/FAAH modulator-1 is a cannabinoid type 2 receptor (CB2R) full agonist with Kis of 14.8 nM and 241.3 nM for CB2R and CB1R, respectively. CB2R/FAAH modulator-1 is a fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 4 μM. CB2R/FAAH modulator-1 decreases pro-inflammatory and increases anti-inflammatory cytokines production[1]. |
| Invitro | CB2R/FAAH modulator-1 (化合物 13; 10 μM; 24 小时) 减少未刺激的单核细胞和巨噬细胞中促炎细胞因子 TNFα、IFN-γ、IL-1β 和 IL6 的产生[1] . |
| Name | CB2R/FAAH modulator-1 |
| CAS | 928892-60-8 |
| Formula | C24H27NO2 |
| Molar Mass | 361.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Francesca Intranuov, et al. Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. J Med Chem. 2023 Jan 12;66(1):235-250. |
CB2R/FAAH modulator-1
CAS: 928892-60-8 F: C24H27NO2 W: 361.48
CB2R/FAAH modulator-1 is a cannabinoid type 2 receptor (CB2R) full agonist with Kis of 14.8 nM and 241.3 nM for CB2R and
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.