| Bioactivity | CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor. CAY 10434 dihydrochloride improves contractile response to angiotensin II with the maximal contractile response (Emax) 6764 mg[1]. |
| Target | CYP4A hydroxylase |
| Invitro | CAY 10434 dihydrochloride (1 µM；30 分钟) 结合咪康唑可增加内皮完整主动脉环中血管紧张素 II 的累积[1]。 |
| Name | CAY 10462 dihydrochloride |
| CAS | 502656-68-0 |
| Formula | C17H27Cl2N3O |
| Molar Mass | 360.32 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Jerez S, et al. 17-Octadecynoic acid improves contractile response to angiotensin II by releasing vasocontrictor prostaglandins. Prostaglandins Other Lipid Mediat. 2012 Jan;97(1-2):36-42. |
CAY 10462 dihydrochloride
CAS: 502656-68-0 F: C17H27Cl2N3O W: 360.32
CAY 10434 dihydrochloride is a potent CYP4A hydroxylase inhibitor. CAY 10434 dihydrochloride improves contractile respon
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