| Bioactivity | CATPB is a potent, selective free fatty acid receptor 2 (FFA2R/GPR43) antagonist[1]. | ||||||||||||
| Target | FFA2R(GPR43) | ||||||||||||
| Invitro | CATPB inhibits the transient rise in intracellular Ca2+ induced in neutrophils by acetate or Cmp1 (FFAR2 agonist)[1]. CATPB inhibits Cmp1-induced NADPH oxidase activity[1]. | ||||||||||||
| Name | CATPB | ||||||||||||
| CAS | 1322598-09-3 | ||||||||||||
| Formula | C19H17ClF3NO3 | ||||||||||||
| Molar Mass | 399.79 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Lena Björkman, et al. The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment. Mol Cell Biol. 2016 |