| Bioactivity | CASIN is a selective GTPase Cdc42 inhibitor with an IC50 of 2 uM. CASIN can be used for the research of cancer[1][2]. | ||||||||||||
| Invitro | CASIN (0-10 μM; 3 d) inhibits the growth of AMO-1, ARH-77, IM-9 , JJN-3, L-363, MOLP-8 and RPMI-8226/S cells[1].CASIN (0-10 μM; 16 h) inhibits melphalan induced FANCD2 mono-ubiquitination in LR5 cells but shows no effect to S cells[1].CASIN (5 μM; 2 d) increases cell apoptosis of bortezomib-resistant MM patient cells[1]. Cell Viability Assay[3] Cell Line: | ||||||||||||
| Name | CASIN | ||||||||||||
| CAS | 425399-05-9 | ||||||||||||
| Formula | C20H22N2O | ||||||||||||
| Molar Mass | 306.40 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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