Bioactivity | CAIX/CAXII-IN-2 (compound 23) is a CAIX/CAXII inhibitor, with Ki values of 8.9 nM and 5.3 nM for CAIX/CAXII, respectively. CAIX/CAXII-IN-2 can be used in cancer research[1]. |
Invitro | CAIX/CAXII-IN-2 (compound 23) (0-1000 μM,72h) 抑制 MDA-MB-231 和 U87MG 细胞增殖,IC50 值分别为 38.8 μM 和 34 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> CAIX/CAXII-IN-2 相关抗体: |
Formula | C16H14N4O2S |
Molar Mass | 326.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Aslan H,et al. Benzenesulfonamide decorated dihydropyrimidin(thi)ones: carbonic anhydrase profiling and antiproliferative activity. RSC Med Chem. 2024 Mar 26;15(6):1929-1941. |