| Bioactivity | CAD204520, a SERCA inhibitor (IC50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL)[1]. |
| CAS | 2682205-20-3 |
| Formula | C23H32F3N3O2 |
| Molar Mass | 439.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Matteo Marchesini, et al. Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol. 2020 Jun 18;27(6):678-697.e13. |
CAD204520
CAS: 2682205-20-3 F: C23H32F3N3O2 W: 439.51
CAD204520, a SERCA inhibitor (IC50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphobla
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