| Bioactivity | C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a C5aR2-selective agonist. C5aR2 agonist P32 has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo[1]. |
| Target | Complement C5a receptor 2 (C5aR2) |
| CAS | 2097449-46-0 |
| Sequence | Ac-Arg-His-Tyr-Pro-Tyr-Trp-Arg |
| Shortening | Ac-RHYPYWR |
| Formula | C54H70N16O11 |
| Molar Mass | 1119.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li XX, et al. Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists. Int Immunopharmacol. 2021 Nov;100:108074. |
C5aR2 agonist P32
CAS: 2097449-46-0 F: C54H70N16O11 W: 1119.23
C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a C5aR2-selective agonist. C5aR2 agonist P32 has been shown to elicit multiple immu
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