| Bioactivity | C3a (70-77) TFA (Complement 3a (70-77) TFA) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a[1][2]. | ||||||
| Invitro | The direct interaction of C3a(70-77) with human mononuclear leukocytes in culture results in a concentration-dependent inhibition of the generation of LIF evoked by mitogens and by the antigen SK-SD[1]. C3a (70-77) induces histamine release and degranulation of rat mast cells, promotes contraction of guinea pig ileal tissue, and enhances vascular permeability in human skin. C3a (70-77) selectively desensitizes ileal smooth muscle to C3a but not to human C5a, a related anaphylatoxin. The cross-desensitization indicates a specific interaction of C3a (70-77) with cellular C3a binding sites[2]. | ||||||
| Name | C3a (70-77) (TFA) | ||||||
| Sequence | Ala-Ser-His-Leu-Gly-Leu-Ala-Arg | ||||||
| Shortening | ASHLGLAR | ||||||
| Formula | C37H62F3N13O12 | ||||||
| Molar Mass | 937.96 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
C3a (70-77) (TFA)
CAS: F: C37H62F3N13O12 W: 937.96
C3a (70-77) TFA (Complement 3a (70-77) TFA) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the sp
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.