C24:1-Ceramide_product_DataBase

Bioactivity	C24:1-Ceramide is one of the most abundant naturally occurring ceramide. Ceramides regulates many diverse biological activities, such as cell apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain[1][2][3].
Invitro	C24:1-Ceramide 可结合磷酸化-Tyr-216-GSK3 (pYGSK3)[4]。C24:1-Ceramide (1 μM, 48 h) 诱导室管膜细胞纤毛伸长[4]。
Name	C24:1-Ceramide
CAS	54164-50-0
Formula	C42H81NO3
Molar Mass	648.10
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Gudz, T.I., et al. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide. The Journal of Biological Chemisty 272(39), 24154-24158 (1997). [2]. ugé, N., et al. The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation. The Journal of Biological Chemisty 271(32), 19251-19255 (1996). [3]. Gu, Q., et al. Ceramide profiling of complex lipid mixtures by electrospray ionization mass spectrometry. Anal. Biochem. 244(2), 347-356 (1997). [4]. Kong JN, et al. Regulation of Chlamydomonas flagella and ependymal cell motile cilia by ceramide-mediated translocation of GSK3. Mol Biol Cell. 2015 Dec 1;26(24):4451-65.

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