| Bioactivity | C16G2 is a specific targeted antimicrobial peptide (STAMP) that targets the cariogenic oral pathogen Streptococcus mutans. C16G2 specifically recognizes and disrupts the bacterial cell membrane, causing small molecule leakage and loss of membrane potential, leading to bacterial killing. Unlike broad-spectrum antimicrobial peptides, C16G2 exhibits higher selectivity and efficacy against Streptococcus mutans[1]. |
| CAS | 2154327-48-5 |
| Sequence | Thr-Phe-Phe-Arg-Leu-Phe-Asn-Arg-Ser-Phe-Thr-Gln-Ala-Leu-Gly-Lys-Gly-Gly-Gly-Lys-Asn-Leu-Arg-Ile-Ile-Arg-Lys-Gly-Ile-His-Ile-Ile-Lys-Lys-Tyr-NH2 |
| Shortening | TFFRLFNRSFTQALGKGGGKNLRIIRKGIHIIKKY-NH2 |
| Formula | C190H310N58O42 |
| Molar Mass | 4078.93 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kaplan CW, et al. Selective membrane disruption: mode of action of C16G2, a specifically targeted antimicrobial peptide. Antimicrob Agents Chemother. 2011 Jul;55(7):3446-52. |
C16G2
CAS: 2154327-48-5 F: C190H310N58O42 W: 4078.93
C16G2 is a specific targeted antimicrobial peptide (STAMP) that targets the cariogenic oral pathogen Streptococcus mutan
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