| Bioactivity | C12-TLRa is an adjuvant lipidoid. C12-TLRa acts as a structural component of LNP to enhance mRNA delivery. C12-TLRa substitution can increase antigen-specific antibody responses and B cell responses of clinically relevant mRNA-LNP vaccines[1]. |
| Name | C12-TLRa |
| Formula | C46H73N5O2 |
| Molar Mass | 728.10 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Han X, et al. Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines. Nat Nanotechnol. 2023 Jun 26. |