Bioactivity | C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids. C12-200 is commonly used for mRNA delivery[1][2]. | ||||||||||||
Name | C12-200 | ||||||||||||
CAS | 1220890-25-4 | ||||||||||||
Formula | C70H145N5O5 | ||||||||||||
Molar Mass | 1136.93 | ||||||||||||
Appearance | Viscous liquid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Khare P, et al. Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells. AAPS J. 2021;24(1):8. Published 2021 Dec 6. [2]. DeRosa F, et al. Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system. Gene Ther. 2016;23(10):699-707. |