| Bioactivity | C-Type Natriuretic Peptide (CNP) (1-22), human, a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor[1][2][3]. | ||||||
| Invitro | C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) (0.01, 0.1, 1, 10, 100, 1000 nM) increases cGMP production in CHO cells expressing human NPR-B in a concentration-dependent manner[1]. | ||||||
| Name | C-Type Natriuretic Peptide (CNP) (1-22), human | ||||||
| CAS | 127869-51-6 | ||||||
| Sequence | Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys (Disulfide bridge: Cys6-Cys22) | ||||||
| Shortening | GLSKGCFGLKLDRIGSMSGLGC (Disulfide bridge: Cys6-Cys22) | ||||||
| Formula | C93H157N27O28S3 | ||||||
| Molar Mass | 2197.60 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
C-Type Natriuretic Peptide (CNP) (1-22), human
CAS: 127869-51-6 F: C93H157N27O28S3 W: 2197.60
C-Type Natriuretic Peptide (CNP) (1-22), human, a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agon
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