| Bioactivity | Butriptyline (Butriptylene) is an orally active tricyclic antidepressant agent[1]. |
| In Vivo | Butriptyline (1000 mg/kg; in diet; 10 weeks) shows anti-obesity effect in mice[1].Butriptyline hydrochloride (2.5-30 mg/kg; i.p.; 10-15 day intervals) causes a dose dependent depression of the food reinforced responses and slightly depresses the avoidance reflex at the highest doses in male albino rats[2]. Animal Model: |
| Name | Butriptyline |
| CAS | 35941-65-2 |
| Formula | C21H27N |
| Molar Mass | 293.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dulloo AG, et al. Screening of drugs for thermogenic anti-obesity properties: antidepressants. Ann Nutr Metab. 1987;31(2):69-80. [2]. Molinengo L, et al. The action of imipramine, amitriptyline, doxepin and butriptyline in an operant conditioning schedule. Psychopharmacologia. 1972;24(2):247-57. |