| Bioactivity | Bursehernin (Methylpluviatolide) is an antitumor agent. Bursehernin induces Apoptosis and cell cycle arrest at G2/M phase. Bursehernin shows anti-proliferative activity[1][2]. |
| Invitro | Bursehernin (4.3 µM for MCF-7 cells, 3.7 µM for KKU-M213 cells; 4, 48, 72 h) 以时间依赖的方式诱导细胞凋亡和细胞周期停滞在G2/M期 [1]。 Cell Proliferation Assay [1] Cell Line: |
| Name | Bursehernin |
| CAS | 40456-51-7 |
| Formula | C21H22O6 |
| Molar Mass | 370.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rattanaburee T, et al. Anticancer activity of synthetic (±)-kusunokinin and its derivative (±)-bursehernin on human cancer cell lines. Biomed Pharmacother. 2019 Sep;117:109115. [2]. McDoniel PB, et al. Antitumor activity of Bursera schlechtendalii (burseraceae): isolation and structure determination of two new lignans. J Pharm Sci. 1972 Dec;61(12):1992-4. |