| Bioactivity | Bumetanide-d5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1]. | |||||||||
| Name | Bumetanide-d5 | |||||||||
| CAS | 1216739-35-3 | |||||||||
| Formula | C17H15D5N2O5S | |||||||||
| Molar Mass | 369.45 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Sandström PE1, et al. Evidence for diabetogenic action of bumetanide in mice.Eur J Pharmacol. 1988 May 20;150(1-2):35-41. |
Bumetanide-d5
CAS: 1216739-35-3 F: C17H15D5N2O5S W: 369.45
Bumetanide-d5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits
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