Bioactivity | Bumetanide (Standard) is the analytical standard of Bumetanide. This product is intended for research and analytical applications. Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively. |
CAS | 28395-03-1 |
Formula | C17H20N2O5S |
Molar Mass | 364.42 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |