Bioactivity | Budigalimab (ABBV 181; PR 1648817) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. Budigalimab is Fc mutated thus to reduce Fc receptor interactions and limit effector function[1]. |
Target | programmed cell death 1 (PD-1) receptor |
Name | Budigalimab |
CAS | 2098225-93-3 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Powderly J, et al. Model Informed Dosing Regimen and Phase I Results of the Anti-PD-1 Antibody Budigalimab (ABBV-181). Clin Transl Sci. 2021 Jan;14(1):277-287. |