Bioactivity | Btk substrate peptide is a peptide substrate corresponding to residues 217-229 of human Bruton’s tyrosine kinase (Btk), of which the tyrosine at residue 223 is the major autophosphorylation site of Btk. Btk substrate peptide is used as a substrate in in vitro kinase assays to evaluate the activity of Btk or other tyrosine kinases[1]. |
Sequence | Lys-Lys-Val-Val-Ala-Leu-Tyr-Asp-Tyr-Met-Pro-Met-Asn |
Shortening | KKVVALYDYMPMN |
Formula | C72H114N16O19S2 |
Molar Mass | 1571.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bence, et al. "Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit." Nature 389.6648 (1997): 296-299. |