| Bioactivity | Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper[1]. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc[2]. | ||||||||||||
| Name | Bruceantinol | ||||||||||||
| CAS | 53729-52-5 | ||||||||||||
| Formula | C30H38O13 | ||||||||||||
| Molar Mass | 606.61 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Bruceantinol
CAS: 53729-52-5 F: C30H38O13 W: 606.61
Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper. Bruceantinol is a STAT
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