Bioactivity | Bruceantarin is a potent antineoplastic agent. Bruceantarin can be used for leukemia and breast cancer research[1][2]. |
Invitro | Bruceantarin exhibits potent antineoplastic activity in both MCF-7 and MDA-MB-231 cells, with IC50 values of 0.144 ± 0.039 μM and 0.238 ± 0.021, respectively[1]. |
Name | Bruceantarin |
CAS | 41451-76-7 |
Formula | C28H30O11 |
Molar Mass | 542.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ye QM, et al. Isolation, chemotaxonomic significance and cytotoxic effects of quassinoids from Brucea javanica. Fitoterapia. 2015 Sep;105:66-72. [2]. Kupchan SM, et al. Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica. J Org Chem. 1973 Jan 12;38(1):178-9. |