| Bioactivity | Brevicidine is a non-ribosomally synthesized antimicrobial peptide with potent antibacterial activity against Gram-negative pathogens. Brevicidine disrupts the morphology of bacteria by binding to polysaccharides (LPS) on bacterial cell membranes to form holes. Brevicidine can be used in antibacterial research[1]. |
| CAS | 2676889-05-5 |
| Sequence | Deamino-Leu(5-Me)-{d-Asn}-{d-Tyr}-{d-Trp}-{d-Orn}-{Orn}-Gly-{d-Orn}-Trp-Thr-Ile-Gly-Ser (Lactone: Trp9-Ser12) |
| Shortening | Deamino-Leu(5-Me)-{d-Asn}-{d-Tyr}-{d-Trp}-{d-Orn}-{Orn}-G-{d-Orn}-WTI GS (Lactone: Trp9-Ser12) |
| Formula | C74H106N18O17 |
| Molar Mass | 1519.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao X, et al. Mimicry of a non-ribosomally produced antimicrobial, brevicidine, by ribosomal synthesis and post-translational modification[J]. Cell Chemical Biology, 2020, 27(10): 1262-1271. e4. |
Brevicidine
CAS: 2676889-05-5 F: C74H106N18O17 W: 1519.74
Brevicidine is a non-ribosomally synthesized antimicrobial peptide with potent antibacterial activity against Gram-negat
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