PeptideDB

Brevetoxin B

CAS: 79580-28-2 F: C50H70O14 W: 895.08

Brevetoxin B (Brevetoxin-2; PbTx-2) is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. Br
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Brevetoxin B (Brevetoxin-2; PbTx-2) is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. Brevetoxin B binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50=15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively.
Name Brevetoxin B
CAS 79580-28-2
Formula C50H70O14
Molar Mass 895.08
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.