Bioactivity | BpV(pic) (potassium hydrate) is a PTEN inhibitor with IC50 31 nM. BpV(pic) (potassium hydrate) is also an insulin simulator that activates insulin receptor kinase in cultured liver cancer cells, stimulates adipogenesis in adipocytes, and inhibits the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors in rat hepatosomes[1][2]. |
CAS | 148556-27-8 |
Formula | C6H8K2NO9V32- |
Molar Mass | 469.15 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Schmid AC,et al. Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Lett. 2004 May 21;566(1-3):35-8. [2]. Posner BI, et al. Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. J Biol Chem. 1994 Feb 11;269(6):4596-604. |