| Bioactivity | Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma[1]. |
| Invitro | Box5 (100 μM) 降低 A2058 细胞中 rWnt5a (0.1 μg/mL) 刺激的 p-MARCKS 的表达[1]。 Western Blot Analysis[1] Cell Line: |
| Name | Box5 |
| CAS | 881188-48-3 |
| Sequence | Met-Asp-Gly-Cys-Glu-Leu |
| Shortening | MDGCEL |
| Formula | C25H42N6O11S2 |
| Molar Mass | 666.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |