| Bioactivity | Boc5 is a non-peptidic glucagon-like peptide-1 receptor agonist. Boc5 causes sustained glycemic control and weight loss in diabetic mice. Boc5 can be used in research of diabetic[1][2]. |
| In Vivo | Boc5 (0.1-3 mg/只小鼠; i.p.; 患有糖尿病的 db/db 小鼠) 具有抗糖尿病活性，并能以剂量依赖性方式改善血糖控制[1]。Boc5 (0.1-3 mg/只小鼠; i.p.; 患有糖尿病的 db/db 小鼠) 具有抗肥胖活性并可减轻糖尿病小鼠的体重[1]。 Animal Model: |
| Name | Boc5 |
| CAS | 917569-14-3 |
| Formula | C54H52N4O16S2 |
| Molar Mass | 1077.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Su H, et, al. Boc5, a non-peptidic glucagon-like Peptide-1 receptor agonist, invokes sustained glycemic control and weight loss in diabetic mice. PLoS One. 2008 Aug 6;3(8):e2892. [2]. He M, et, al. A continued saga of Boc5, the first non-peptidic glucagon-like peptide-1 receptor agonist with in vivo activities. Acta Pharmacol Sin. 2012 Feb;33(2):148-54. |