| Bioactivity | Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | ||||||||||||
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. | ||||||||||||
| Name | Boc-NH-PEG6-CH2CH2COOH | ||||||||||||
| CAS | 882847-13-4 | ||||||||||||
| Formula | C20H39NO10 | ||||||||||||
| Molar Mass | 453.52 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Boc-NH-PEG6-CH2CH2COOH
CAS: 882847-13-4 F: C20H39NO10 W: 453.52
Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG6-CH2CH2
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