| Bioactivity | Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1]. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[2]. | ||||||||||||
| Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||
| Name | Boc-NH-PEG4-CH2CH2COOH | ||||||||||||
| CAS | 756525-91-4 | ||||||||||||
| Formula | C16H31NO8 | ||||||||||||
| Molar Mass | 365.42 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Boc-NH-PEG4-CH2CH2COOH
CAS: 756525-91-4 F: C16H31NO8 W: 365.42
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is al
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