| Bioactivity | Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays[1][2]. | ||||||
| Invitro | To demonstrate the presence in the abdominal gland of proteolytic enzymes capable of generating Sodefrin, an enzymatic assay was developed using Boc-Leu-Gly-Arg-AMC as synthetic substrate. A crude extract of the abdominal gland hydrolyzed Boc-Leu-Gly-Arg-AMC to liberate 7-amino-4- methylcoumarin, suggesting that enzymes that generate sodefrin from its precursor molecule are present in the gland. The activity in the extract for cleaving Boc-Leu-Gly-Arg-AMC is optimal at pH 9.0 and 45 ℃[1]. | ||||||
| Name | Boc-Leu-Gly-Arg-AMC | ||||||
| CAS | 65147-09-3 | ||||||
| Sequence | Boc-Leu-Gly-Arg-AMC | ||||||
| Shortening | Boc-LGR-AMC | ||||||
| Formula | C29H43N7O7 | ||||||
| Molar Mass | 601.69 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Boc-Leu-Gly-Arg-AMC
CAS: 65147-09-3 F: C29H43N7O7 W: 601.69
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic ass
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