Bioactivity | Bleformin A is a potent BChE inhibitor with an IC50 value of 5.2 μM. Bleformin A is a nature product that could be isolated from Bletilla striata. Bleformin A can be used for research of Alzheimer's disease (AD)[1]. |
Invitro | Bleformin A (compound 8; 0-8.302 μM) inhibits BChE with a Ki value of 4.7 μM. Bleformin A decreases Vmax and increases Km in a dose-dependent manner[1]. |
Name | Bleformin A |
CAS | 1980064-35-4 |
Formula | C23H20O5 |
Molar Mass | 376.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liu Y, et, al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649. |