| Bioactivity | Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM[1]. |
| Invitro | Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride; Ro31-8425 hydrochloride) derivatives acts as an useful tool to compare inhibitor potencies and selectivities for a target of interest[1]. |
| Name | Bisindolylmaleimide X hydrochloride |
| CAS | 145317-11-9 |
| Formula | C26H25ClN4O2 |
| Molar Mass | 460.96 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Brehmer D, et al. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol Cell Proteomics. 2004 May;3(5):490-500. |
Bisindolylmaleimide X hydrochloride
CAS: 145317-11-9 F: C26H25ClN4O2 W: 460.96
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective protein kinase C (PKC) inhibitor. Bi
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