Bischloroanthrabenzoxocinone_product_DataBase

Bioactivity	Bischloroanthrabenzoxocinone is a potent Type II fatty acid synthesis (FASII) inhibitor. Bischloroanthrabenzoxocinone inhibits fatty acid synthesis. Bischloroanthrabenzoxocinone shows antibacterial activities and inhibits phospholipid, DNA, RNA, protein, and cell wall synthesis[1].
Invitro	Bischloroanthrabenzoxocinone (0.01-333 µg/mL) 抑制脂肪酸合成，对 Staphylococcus aureus 和 Escherichia coli 的 IC50 值分别为 11.4、35.3 µg/mL[1].Bischloroanthrabenzoxocinone (0-250 µg/mL) 显示出抗菌活性，对 Staphylococcus aureus 和野生型 Escherichia coli 的 MIC 值分别为 0.2、>250 µg/mL [1].Iscloroanthrabenzoxocinone 抑制磷脂合成，IC50 值为 0.21 μg/ml，它还抑制 Staphylococcus aureus 和 Escherichia coli 中的 DNA、RNA、蛋白质和细胞壁合成[1]。
Name	Bischloroanthrabenzoxocinone
CAS	866022-28-8
Formula	C28H24Cl2O7
Molar Mass	543.39
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Kodali S, et al. Determination of selectivity and efficacy of fatty acid synthesis inhibitors. J Biol Chem. 2005 Jan 14;280(2):1669-77.

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