| Bioactivity | Bis-propargyl-PEG9 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG9 can be used to synthesize the bivalent estrogen receptor ligands[1]. |
| Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Name | Bis-propargyl-PEG9 |
| CAS | 1351373-47-1 |
| Formula | C24H42O10 |
| Molar Mass | 490.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shan M, et al. Conformational analysis of bivalent estrogen receptor ligands: from intramolecular to intermolecular binding. Chembiochem. 2011 Nov 25;12(17):2587-98. |
Bis-propargyl-PEG9
CAS: 1351373-47-1 F: C24H42O10 W: 490.58
Bis-propargyl-PEG9 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG9 can be used to synt
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