Bis-propargyl-PEG4_product_DataBase

CAS: 159428-42-9 F: C14H22O5 W: 270.32

Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the syn

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers[1][2].

Invitro

Bis-propargyl-PEG4 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].

Name

Bis-propargyl-PEG4

CAS

159428-42-9

Formula

C14H22O5

Molar Mass

270.32

Appearance

Liquid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2. [2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.

PeptideDB

Bis-propargyl-PEG4

CAS: 159428-42-9 F: C14H22O5 W: 270.32