| Bioactivity | Biotin-labeled ODN 1826, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled ODN 1826 can?be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy. |
| Name | Biotin-labeled ODN 1826 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Krogmann AO, et al. Proinflammatory Stimulation of Toll-Like Receptor 9 with High Dose CpG ODN 1826 Impairs Endothelial Regeneration and Promotes Atherosclerosis in Mice. PLoS One. 2016 Jan 11;11(1):e0146326. [2]. Utaisincharoen P, et al. CpG ODN activates NO and iNOS production in mouse macrophage cell line (RAW 264.7). Clin Exp Immunol. 2002 Jun;128(3):467-73. [3]. Yuan S, et al. CpG oligodeoxynucleotide 1826 enhances the Lewis lung cancer response to radiotherapy in murine tumor. Cancer Biother Radiopharm. 2011 Apr;26(2):203-8. |