| Bioactivity | Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA)[1][2]. |
| CAS | 365441-71-0 |
| Formula | (C2H4O)nC19H28N4O7S |
| Appearance | 粘稠液体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Maldiney T, et al. In vitro targeting of avidin-expressing glioma cells with biotinylated persistent luminescence nanoparticles. Bioconjug Chem. 2012 Mar 21;23(3):472-8. [2]. Deng D, et al. Biotin-Avidin System-Based Delivery Enhances the Therapeutic Performance of MSC-Derived Exosomes. ACS Nano. 2023 May 9;17(9):8530-8550. |
Biotin-PEGn-NHS ester
CAS: 365441-71-0 F: (C2H4O)nC19H28N4O7S W:
Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PR
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