| Bioactivity | Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Name | Biotin-PEG2-acid |
| CAS | 1365655-89-5 |
| Formula | C17H29N3O6S |
| Molar Mass | 403.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light, stored under argon *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon) |
Biotin-PEG2-acid
CAS: 1365655-89-5 F: C17H29N3O6S W: 403.49
Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biot
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