Bioactivity | Bio-AMS is a potent bacterial biotin protein ligase inhibitor. Bio-AMS possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis[1][2]. |
Name | Bio-AMS |
CAS | 1393881-52-1 |
Formula | C20H29N9O7S2 |
Molar Mass | 571.63 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bockman MR, Aldrich CC, et al. Avoiding Antibiotic Inactivation in Mycobacterium tuberculosis by Rv3406 through Strategic Nucleoside Modification. ACS Infect Dis. 2018 Jul 13;4(7):1102-1113. [2]. Tiwari D, et al. Targeting protein biotinylation enhances tuberculosis chemotherapy. Sci Transl Med. 2018 Apr 25;10(438):eaal1803. |