Bioactivity | Bim BH3, Peptide IV TFA is a 26-residue peptide from BH3-only protein Bim, which belongs to the pro-apoptotic group of the Bcl-2 family of proteins[1][2]. |
Name | Bim BH3, Peptide IV TFA |
Sequence | Asp-Met-Arg-Pro-Glu-Ile-Trp-Ile-Ala-Gln-Glu-Leu-Arg-Arg-Ile-Gly-Asp-Glu-Phe-Asn-Ala-Tyr-Tyr-Ala-Arg-Arg |
Shortening | DMRPEIWIAQELRRIGDEFNAYYARR |
Formula | C147H223N44F3O43S |
Molar Mass | 3383.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhu Y, et al. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondriain T cells. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7681-6. [2]. Lee EF, et al. High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL. Angew Chem Int Ed Engl. 2009;48(24):4318-22. |