| Bioactivity | Big Endothelin-1 (22-38), human is derived from human, is the 22-38 fragment of Big Endothelin-1 (ET-1) (1-38). Big ET-1 (1-38) is a propeptide of ET-1, which has potent and long-lasting vasoconstrictor effects, equips a specific enzymatic cleavage of the 38 amino acid chain to form ET-1 (1-21) and the C-terminal fragment Big ET-1 (22-38)[1]. |
| Invitro | Big Endothelin-1 (22-38), human (0.1 μM; 30 min) induces the release of prostacyclin (PGI2) from rabbit, guinea pig, and rat lungs[2]. |
| Name | Big Endothelin-1 (22-38), human |
| CAS | 124932-61-2 |
| Shortening | VNTPEHVVPYGLGSPRS |
| Formula | C80H125N23O25 |
| Molar Mass | 1808.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Big Endothelin-1 (22-38), human
CAS: 124932-61-2 F: C80H125N23O25 W: 1808.99
Big Endothelin-1 (22-38), human is derived from human, is the 22-38 fragment of Big Endothelin-1 (ET-1) (1-38). Big ET-1
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