| Bioactivity | Bicyclic UK18 is a competitive inhibitor for human urokinase-type plasminogen activator (uPA) with a Ki of 53 nM[1]. |
| CAS | 1393680-45-9 |
| Sequence | Ala-Cys-Ser-Arg-Tyr-Glu-Val-Asp-Cys-Arg-Gly-Arg-Gly-Ser-Ala-Cys-Gly (cyclized via TBMB and Cys2,9,16) |
| Shortening | ACSRYEVDCRGRGSACG (cyclized via TBMB and Cys2,9,16) |
| Formula | C77H118N26O25S3 |
| Molar Mass | 1904.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Angelini A, et al., Bicyclic peptide inhibitor reveals large contact interface with a protease target. ACS Chem Biol. 2012 May 18;7(5):817-21. |
Bicyclic UK18
CAS: 1393680-45-9 F: C77H118N26O25S3 W: 1904.12
Bicyclic UK18 is a competitive inhibitor for human urokinase-type plasminogen activator (uPA) with a Ki of 53 nM.
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