Bioactivity | Bicuculline (Standard) is the analytical standard of Bicuculline. This product is intended for research and analytical applications. Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice. |
CAS | 485-49-4 |
Formula | C20H17NO6 |
Molar Mass | 367.35 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |