| Bioactivity | Bfl-1-IN-5 (Compound (R,R,S)-26) is a selective inhibitor for Bfl-1 with an IC50 of 0.022 μM. Bfl-1-IN-5 promotes the caspase-3/7 activity with an EC50 of 0.37 μM, and inhibits the cell viability of SU-DHL-1 with an EC50 of 1.3 μM[1]. |
| Formula | C24H24F3N3O2 |
| Molar Mass | 443.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lucas SCC, et al., Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors. J Med Chem. 2024 Sep 26;67(18):16455-16479. |