| Bioactivity | Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca2+ antagonist[1][2]. |
| Invitro | Bevantolol hydrochloride has a pKi of 6.23 for β2-adrenergic receptor[1]. |
| In Vivo | Bevantolol hydrochloride (200 mg/kg; PO by water; for 6 weeks) produces a significant decrease in the expression level of β1 adrenoceptor mRNA[2]. Animal Model: |
| Name | Bevantolol hydrochloride |
| CAS | 42864-78-8 |
| Formula | C20H28ClNO4 |
| Molar Mass | 381.89 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. M Takita, et al. Selectivity of Bevantolol Hydrochloride Towards Alpha- And Beta-Adrenoceptor Subtypes in Rat Cerebral Cortex. Jpn J Pharmacol. 1992 Feb;58(2):193-6. [2]. Takahiro Horinouchi, et al. Different Changes of Plasma Membrane Beta-Adrenoceptors in Rat Heart After Chronic Administration of Propranolol, Atenolol and Bevantolol. Life Sci. 2007 Jul 12;81(5):399-404. |
Bevantolol hydrochloride
CAS: 42864-78-8 F: C20H28ClNO4 W: 381.89
Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat c
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.