Bioactivity | Benastatin C is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; IC50=24 μg/mL for the rat liver enzyme).2 Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC50=10 μg/mL). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner. |
CAS | 150151-88-5 |
Formula | C29H28O5 |
Molar Mass | 456.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xu, et al. Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids. J. Am. Chem. Soc. 129(18), 6022-6030 (2007). |