| Bioactivity | Beclobrate (Sgd 24774), a Fibric acid derivative, displays remarkable lipid lowering activity in rodents[1]. |
| In Vivo | On the normal diet rats, Beclobrate lowers total plasma cholesterol by 22-33.4% (10-50 mg/kg); the cholesterol reduction occurred mainly in high density lipoproteins (HDL). In addition, Beclobrate administration dramatically increases the activity of the high-affinity receptors for beta-VLDL in isolated liver membranes[1]. |
| Name | Beclobrate |
| CAS | 55937-99-0 |
| Formula | C20H23ClO3 |
| Molar Mass | 346.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. C Manzoni, et al. Differential effects of beclobrate on lipid/lipoprotein distribution in normal and hypercholesterolemic rats. Eur J Pharmacol. 1990 Nov 6;190(1-2):39-49. |